Harry Osborn was good friends with Peter Parker during high school and started a love interest with Mary Jane. After believing his father's death was caused by Spider-Man, Harry Osborn spent two years trying to find him. Harry took over Oscorp and supported Doctor Octavius's fusion experiments. After Ock's transformation, Harry made a deal with Doc Ock to bring Spider-Man to him alive, where he unmasked him and discovered his true identity, Peter Parker. He then took his boat and helped him save Mary Jane from Doc Ock.